As early as the 12th century, the Waldensian Christians outside the church identified the "little horn" and "Man of Sin" as the Roman Papacy. But even within the church, among the most learned godly men, Papacy also became increasingly identified as "Anti-Christ" and the "Man of Sin."

Pre-Reformation Interpretations:

The detector of error having been removed, Satan worked according to his will. Prophecy had declared that the papacy was to “think to change times and laws.” Daniel 7:25. This work it was not slow to attempt. To afford converts from heathenism a substitute for the worship of idols, and thus to promote their nominal acceptance of Christianity, the adoration of images and relics was gradually introduced into the Christian worship. The decree of a general council [Second Council of Nice, A.D. 787]

Exodus Chapter 20

2 I am the LORD thy God, which have brought thee out of the land of Egypt, out of the house of bondage.
3 Thou shalt have no other gods before me.
4 Thou shalt not make unto thee any graven image, or any likeness of any thing that is in heaven above, or that is in the earth beneath, or that is in the water under the earth:
5 Thou shalt not bow down thyself to them, nor serve them: for I the LORD thy God am a jealous God, visiting the iniquity of the fathers upon the children unto...

Great blessings are enfolded in the observance of the Sabbath, and God desires that the Sabbath day shall be to us a day of joy. There was joy at the institution of the Sabbath. God looked with satisfaction upon the work of His hands. All things that He had made He pronounced “very good.” Genesis 1:31. Heaven and earth were filled with rejoicing. “The morning stars sang together, and all the sons of God shouted for joy.” Job 38:7. Though sin has entered the world to mar His perfect work, God...